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Hexyl nicotinate CAS 23597-82-2

Hexyl nicotinate is a nicotinate ester derived from niacin. It is an oil-soluble compound with a favorable lipophilic character that enables good skin penetration.

Core positioning: Gentle brightening · Low-irritation soothing · Moderate lipophilicity · Long-lasting compatibility · Sensitive-skin friendly


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Nicotinic acid hexyl ester Topical vasodilator Anti-cellulite and body contouring Improves microcirculation Muscle and joint pain relief

Basic Information

Product Description

CAS No.	23597-82-2
EINECS	245-767-4
Synonym	Nicotinic acid hexyl ester; n-Hexyl nicotinate; Hexyl 3-pyridinecarboxylate
Molecular Formula	C₁₂H₁₇NO₂
Molecular Weight	207.27
Appearance	Colorless clear liquid
Odor	Very slight characteristic odor
Flash Point	127.8°C
Boiling Point	140°C
Purity	≥98.0%(GC)
Density and/or relative density	1.02g/cm3
Solubility	Stable at room temperature; recommended in a cool, dark place; can be stored under inert atmosphere to prevent discoloration

【Core Advantages】

Microcirculation Improvement: Significant vasodilation effect improves periorbital circulation (helps reduce dark circles), promotes facial and scalp blood flow, suitable for dull skin with insufficient blood supply and anti-aging scalp care scenarios.
Barrier Repair & Anti-Aging: Niacin provides raw material for NAD+ synthesis, supports cellular energy metabolism, stimulates stratum corneum lipid synthesis, strengthens skin barrier; helps improve photodamage and fine lines caused by dryness, delaying skin aging.
Brightening & Soothing Dual Action: Reduces melanin deposition, helps brighten complexion and improve dullness; simultaneously inhibits inflammatory factors, alleviates redness and itching in sensitive skin, suitable for daily care of compromised skin barriers.
Low Irritation & Gentle, Wide Suitability: Compared with niacin and myristyl nicotinate, it has lower irritation and moderate lipophilicity, making it more suitable for sensitive skin and long-term daily care, compatible with all skin types.

【Product Features】

Good Oil Solubility, Strong Adaptability: Easy to add to oil phase, creams, facial oils, eye creams, body lotions, etc.; good formulation compatibility, no complex pretreatment required.
Light Texture, Excellent Sensory Experience: Non-greasy texture, does not affect the original skin feel of the product, suitable for various skincare scenarios.
Good Stability: Can be stored at room temperature without special storage conditions, reducing formulation waste, easy and worry-free to use.

【Applications & Recommended Dosage】

Application Scenario	Typical Products	Recommended Dosage
Facial Skincare	Brightening serums, firming creams, lotions, exfoliating products	0.2%–0.4% (conventional gentle range)
Eye Care	Eye creams, eye serums	0.2%–0.3% (lower irritation, focus on microcirculation)
Scalp Care	Scalp serums, conditioners	0.2%–0.3%
Body Care	Brightening body lotions, anti-edema products	0.2%–0.4%
High-Efficacy Products	High-brightening, anti-edema products	Up to 0.46% (regulatory upper limit)