Alverine citrate API is the citrate salt of alverine, a smooth muscle antispasmodic agent. It appears as white to off-white crystalline powder.
It exerts a direct relaxant effect on smooth muscle tissues, mainly the gastrointestinal and uterine smooth muscle, by regulating calcium influx in smooth muscle cells, without typical anticholinergic adverse reactions such as dry mouth.
Application
Treatment of Irritable Bowel Syndrome (IBS)
Alverine Citrate directly acts on the intestinal smooth muscle to relax it, thereby alleviating symptoms such as pain, bloating, constipation, or diarrhea caused by intestinal muscle spasms.
Relief of Pain Caused by Diverticulitis
Diverticulitis is a condition where small pouches form on the inner lining of the large intestine, which can become blocked by food residues and cause inflammation and pain. Alverine Citrate helps to relieve this pain.
Relief of Menstrual Cramps
Alverine Citrate can also relax the uterine smooth muscle, and is therefore used to treat primary dysmenorrhea caused by uterine muscle spasms.
Other Applications
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Drug Synergism Research: Alverine Citrate has been used in research to explore synergistic effects with other drugs (such as fluconazole).
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Energy Metabolism Research: It is used to study the impact of drugs on energy metabolism.
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Signal Transduction Network Research: The drug's effects are studied from the perspective of signal transduction networks.
Packaging
25kg/drum
Handling and Storage
Handling: Use with adequate ventilation.Avoid contact with skin and eyes.Do not breathe dust, vapor, mist, or gas. Take precautionary measures against static discharges.
Storage: Store in a tightly closed container. Store in a dry area.