Ketoprofen is a propionic acid-class non-steroidal anti-inflammatory active pharmaceutical ingredient (API), supplied as a white crystalline powder. It is a racemic mixture; the S-enantiomer contributes the main pharmacological activity.
Ketoprofen API is used to manufacture oral capsules, tablets, topical gels, patches and other formulations. It is indicated for symptomatic relief of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, soft tissue injuries, postoperative pain, primary dysmenorrhea, toothache and fever. It features good skin penetration and is widely adopted in transdermal preparations.
Application
1.Pain Relief
Ketoprofen can be used to relieve mild to moderate pain, including dental pain, menstrual pain, migraines, neuropathic pain, postoperative pain, and osteoarthritis. It is also used to treat pain caused by rheumatic diseases, musculoskeletal disorders, and acute gout.
2.Anti-inflammatory Effects
Ketoprofen exerts anti-inflammatory effects by inhibiting the production of prostaglandins. It is suitable for treating joint swelling and pain caused by rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and other inflammatory conditions.
3.Antipyretic Effects
Ketoprofen has antipyretic properties and can be used to reduce fever caused by infections or inflammation.
4.Topical Applications
Ketoprofen is also available in forms such as patches for topical use, which can help relieve symptoms of rheumatoid arthritis, osteoarthritis, and other related conditions.
Precautions
Keep away from heat. Keep away from sources of ignition. Ground all equipment containing
material. Do not ingest. Do not breathe dust. Wear suitable protective clothing. In case of
insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice
immediately and show the container or the label. Avoid contact with skin and eyes. Keep away
from incompatibles such as oxidizing agents.
Storage
Keep container tightly closed.Keep container in a cool,well-ventilated area.
