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Prednisolone sodium phosphate is a synthetic corticosteroid used to treat a variety of inflammatory, autoimmune, and hormonal conditions. It works by suppressing the body’s immune response and reducing inflammation.
Application
1. Anti-inflammatory and Immunosuppressive Effects
Anti-inflammatory Action: Prednisolone Sodium Phosphate can reduce and prevent the body’s inflammatory response, thereby alleviating the symptoms of inflammation.
Immunosuppressive Action: It can prevent or inhibit cell-mediated immune responses, delay allergic reactions, and reduce the spread of primary immune responses.
2. Ophthalmic Applications
Ophthalmic Solutions: Prednisolone Sodium Phosphate is commonly used to treat short-term inflammatory eye diseases, helping to alleviate eye inflammation, redness, and irritation. It is an ophthalmic drug used to reduce eye inflammation.
3. Injectable Preparations
Anti-inflammatory/Immunosuppressive Injectable Preparations: Prednisolone Sodium Phosphate can be used to prepare injectable preparations for anti-inflammatory and immunosuppressive treatments.
4. Dermatological Preparations
Dermatological Preparations: Prednisolone Sodium Phosphate can also be used to prepare dermatological preparations for the treatment of various skin inflammations.
5. Oral Preparations
Oral Solutions: The oral solution of Prednisolone Sodium Phosphate can be used to treat various diseases that require corticosteroid therapy.
6. Pediatric Applications
Pediatric Drugs: Prednisolone Sodium Phosphate is also used in pediatrics, for example, to treat inflammatory diseases in children.
7. Other Applications
Allergic Reactions: Prednisolone Sodium Phosphate also has anti-allergic effects and can be used to treat allergic diseases.
Storage
Store at roomtemperature.
Keep away from heat, sparks and ignition sources. Keep in well- sealed labelled containers away from light.
Keep in a ventilated place. Avoid direct sun light. Avoid static discharges formation.
Store in accordance with all current regulations and standards.
Stability and Reactivity
Reactivity: The substance is an organic compound,may create in particular conditions (ex.temperature, pressure,
powder granulometry, humidity, oxygen concentration) explosive mixtures with air. In case of accidental
release remove all sources of ignition and ventilate gradually the area.
Chemical stability: The substance is stable in normal conditions of temperature and pressure and if stocked in closed containers in cold and ventilated area.
Possibility of hazardous reactions: The substance is an organic compound, may create in particular conditions (ex. temperature,pressure,powder granulometry, humidity, oxygen concentration) explosive mixtures with air. In case of accidental release, remove all sources of ignition and ventilate gradually the area.
Conditions to avoid: Keep away from heat, flames, sources of ignition and static discharges.
Incompatible materials: Strong oxidizing agents, acids and bases.
Hazardous decomposition products: When heated to decomposition or under fire conditions material emits toxic fumes of carbon monoxide and carbon dioxide gas.
CAS No. | 125-02-0 |
Synonym | Prednisolone 21-(disodium phosphate) Prednisolone phosphate sodium (11b)-11,17-Dihydroxy-21-(phosphonooxy)-pregna-1,4-diene-3,20-dionedisodiumsalt; Disodium prednisolone 21-phosphate |
EINECS No. | 204-722-9 |
Molecular Formula | C21H27Na2O8P |
Molecular Weight | 484.39 |
Appearance | White or almost white crystalline powder |
Assay (%) | 96~103 |
Water(%) | 8max |
Specific Optical Rotation | +94°~+100° |
Solubility | Soluble in water, very slightly soluble in ethanol |