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Myristyl nicotinate is a personal care ingredient that deliver long-lasting antioxidant and anti-aging effects. It's an ester formed from nicotinic acid (vitamin B3) and myristyl alcohol, a 14-carbon saturated fatty alcohol. It is a lipophilic prodrug derivative of nicotinic acid designed to deliver the benefits of vitamin B3 into the skin without causing the irritation or flushing commonly associated with nicotinic acid. It can help strengthen the skin barrier.
Core Positioning: Anti-aging & Brightening · Skin Barrier Repair · Oil Control & Anti-inflammatory · Gentle Skincare
Microcirculation Improvement: Nicotinic acid dilates blood vessels and promotes blood flow, suitable for eye creams (improves dark circles) and scalp care (supports hair retention), with a gentle, non-irritating profile.
Anti-aging and rejuvenation: Boosts cellular NAD+ levels to support energy metabolism and work synergistically against aging; improves microcirculation to help brighten complexion, reduce dullness, and alleviate tired-looking skin.
Firming & Wrinkle Reduction: Enhances skin oxygenation and metabolism, supports collagen synthesis, effectively reduces fine lines and sagging, and restores skin firmness.
Barrier Repair: Stimulates epidermal differentiation in photodamaged skin, increases skin NAD content, and strengthens the skin barrier. Suitable for chronic photodamage, atopic dermatitis, and post-procedure repair.
Applicable Products: Serums, creams, eye creams, neck creams, body lotions, firming lotions
Recommended Addition Rate: 0.5% – 2%
Gentle & Low Irritation: Compared to nicotinic acid (vitamin B3), it is less likely to cause skin irritation and flushing, making it suitable for a wide range of skin types, including sensitive skin.
Broad Oil-Soluble Compatibility: Ideal for oil-phase formulations such as creams, facial oils, and eye creams, offering strong formulation versatility.
Excellent Skin Feel: Smooth texture, non-sticky, enhances product emollience and improves the user experience.
Good Stability: Can be stored for extended periods at room temperature away from light, requiring no special storage conditions and reducing formulation waste.
Good Solubility: Readily soluble in oils and alcohols, insoluble in water, facilitating easy formulation preparation.
Gentle anti-aging · Barrier repair · Outstanding skin feel · Worry-free formula · Multi-scenario compatibility
| CAS No. | 273203-62-9 |
| Synonym | Myristyl nicotinate Niacin Myristate Tetradecyl nicotinate 3-Pyridinecarboxylic acid, tetradecyl ester |
| Molecular Formula | C20H33NO2 |
| Molecular Weight | 319.48 |
| Appearance | White solid powder |
| Odor | Odorless |
| Flash Point | 202.8℃ |
| Boiling Point | 411.7ºC at 760mmHg |
| Purity | ≥98.0%(GC) |
| Density and/or relative density | 0.953g/cm3 |
| Solubility | ≥27.7 mg/mL in DMSO; ≥40.9 mg/mL in ethanol; insoluble in water. |
