| Availability: | |
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| CAS No. | 564-20-5 |
| Synonym | Clareolide Norambreinolide Norambreinolide |
| EINECS | 209-269-0 |
| Molecular Formula | C16H26O2 |
| Specific optical rotation | +44°~ 51° |
| Appearance | White to off-white solid |
| Aroma description | Light Amber aroma and soft woody odor |
| Melting Point(℃) | 120-126 |
| Content(%) | ≥98.0 |
| Shelf life | 12 months |
Sclareolide is a highly valued ingredient in perfumery. It is renowned for its musk-like odor, which is soft, sweet, and slightly ambergris-like, often described as having warm, creamy, and slightly woody character.Its odor strength is medium, with aromatic, woody, cedar-like, and tobacco nuances, along with a mushroom and earthy undertone.
Key functional roles in fragrances include:
Fixative: Sclareolide enhances the longevity and depth of other fragrance components.
Base Note: Due to its low volatility, it primarily contributes to the base notes of a fragrance.
Versatility: It is used across various fragrance families, including oriental, woody, and floral compositions.
Concentration: Typical use concentrations range from 0.1% to 1% in finished products.
Sclareolide is also used as a flavoring agent, primarily as a background note to enhance the richness and depth of flavor profiles, especially in sweet and creamy applications. It is used in the food industry to enhance the flavor of various products, including beverages and confections.Typical use levels in food and beverages are very low, often in the range of 0.1 to 1 ppm, and it is stable under standard food processing conditions
One of the most commercially significant applications of sclareolide is as a key chemical intermediate in the synthesis of Ambrox® (Ambroxan). Ambrox® is a highly prized fragrance ingredient that serves as a sustainable, synthetic alternative to natural ambergris, a rare and expensive substance derived from sperm whales.
In cosmetics, sclareolide is incorporated into skincare products for its aromatic properties. Some research suggests it may also offer antioxidant properties, helping to protect the skin from environmental damage.It is commonly derived from plant sources like clary sage and is used to enhance a formula's scent and boost the longevity of other fragrances。
Pharmaceutical Research: Sclareolide has been investigated for potential therapeutic properties, including anti-inflammatory and antimicrobial activities, making it a candidate for drug development.
Natural Insect Repellent: It has been explored as a component in developing natural insect repellents, offering a potential alternative to synthetic chemicals.
Nutraceuticals: It has been marketed as a weight loss supplement, though no clinical evidence currently supports this effect.
Storage Condition
Store in cool place, keep container tightly closed in a dry and well-ventilated place.