Vitamin K1, scientifically known as Phytonadione, is a fat-soluble vitamin that is synthetically produced to be identical to the naturally occurring form of Vitamin K found in plants. Its chemical name is 2-Methyl-3-phytyl-1,4-naphthoquinone. It is the primary form of Vitamin K used in human therapeutics.
Key Characteristics:
Appearance: A clear, yellow to amber, viscous liquid.
Solubility: It is insoluble in water but soluble in chloroform, ether, and vegetable oils. This reflects its fat-soluble nature.
Stability: It is sensitive to light and alkalis but is stable in air.
Function: It is an essential cofactor for the synthesis of several proteins required for blood coagulation (clotting), such as prothrombin. It is also crucial for bone metabolism and vascular health.
Primary Uses and Applications:
Therapeutic Agent: Its primary use is in medicine to treat and prevent bleeding disorders caused by Vitamin K deficiency.
Newborns: Routinely administered to newborns to prevent Vitamin K Deficiency Bleeding (VKDB), as they are born with low stores of the vitamin.
Antidote: Used as an antidote to counteract the effects of certain blood-thinning medications like warfarin (an anticoagulant) in cases of overdose or to reverse their effects before surgery.
Malabsorption: Used to treat deficiency in conditions like obstructive jaundice, celiac disease, or ulcerative colitis.
Dietary Supplement: Used in nutritional supplements to ensure adequate Vitamin K intake.
Storage:
Storage in dry,cool and well-ventilated place;
Keep container tighted closed;
Keep away from heat/sparks/open flames/heat places;
Store away from incompatible material and foodstuff containers.
