| Availability: | |
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| CAS No. | 2179-57-9 |
| Synonym | Allyl disulfide DADS 4,5-Dithia-1,7-octadiene |
| FEMA No. | 2028 |
| EINECS | 218-548-6 |
| Molecular Formula | C₆H₁₀S₂ |
| Molecular Weight(g/mol) | 146.27 |
| Density(g/cm3) | 1.008 at 25℃ |
| Appearance | Colorless to pale yellow liquid |
| Refractive Index (nD²⁰) | 1.52 |
| Boiling Point(℃) | 180-195 |
| Flashing Point(℃) | 62.2 |
| Solubility | Insoluble in water; soluble in organic solvents such as ethanol, DMSO, and oils. |
Natural Sources
This compound is a major constituent of the essential oil of garlic (Allium sativum) and is also found in onions, chives, and other species of the genus Allium.
Applications and Uses
Flavoring Agent: Due to its potent garlic-like aroma, it is used as a flavoring ingredient in foods, condiments, gravies, and meats. The FDA approves its use in food (21 CFR 172.515) .
Biological Research: It is studied for its potential therapeutic properties, including anticancer, antimicrobial, and cardiovascular protective effects .
Mechanism of Action: In biological systems, DADS acts as a thiol-dependent hydrogen sulfide (H₂S) donor, which is believed to contribute to its cardio- and neuro-protective effects.
Storage and Handling
The compound is flammable and should be stored away from oxidizing agents. It is recommended to store it in a cool, dry place (2-8°C) in a tightly sealed container, protected from light and air to prevent oxidation.